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Research
Professor, IoG 300 North Ingalls |
Duties:
Director of the Analysis Core in the "Genetics of Age-Sensitive
Traits in Mice" Program Project.
Co-Director for the Methodology, Data Management and Analysis Core
of the Older Americans Independence Center.
Co-Director for the Genomics and Analysis Core
of the Older Americans Independence Center.
Research interests:
Applications of modern statistical methods for the analysis of data
from a wide range of gerontological and geriatric studies, including:
- clinical trials,
- epidemiological studies,
- genetic studies,
- survey sampling.
Methodological and analytical issues related to:
- mixed effects models,
- population pharmacokinetics and pharmacodynamics (PK/PD)
- modeling covariance structures.
Web Site Links:
Selected Publications:
Galecki, A.T., Wolfinger, R.D., Linares, O.A., Smith, M.J., Halter,
J.B. (2004)
Ordinary differential equation PK/PD models using the SAS macro NLINMIX
Journal of Biopharmaceutical Statistics 14, 483-504.
Xu, S., Yi, N., Burke, D.T., Galecki, A.T., Miller, R.A. (2003)
An EM algorithm for mapping binary disease loci: application to
fibrosarcoma in a four-way cross mouse family.
Genetical Research 82, 127-138.
Miller, R.A., Chang Y., Galecki, A.T., Al-Regaiey, K., Kopchick, J.,
Bartke, A. (2002) Gene Expression Patterns in Calorically Restricted
Mice: Partial Overlap With Long-Lived Mutant Mice Molecular
Endocrinology 16, 2657-2666.
Jackson, A.U., Galecki, A.T., Burke, D.T., and Miller, R.A.(2003)
Genetic polymorphisms in mouse genes regulating age-sensitive and
age-stable T cell subsets, Genes and Immunity 1, 30-39.
Galecki, A.T., Ten Have, T.R., and Molenberghs, G. (2001) A simple and
fast alternative to the EM algorithm for incomplete categorical data and
latent class models. Computational Statistics and Data Analysis, 35,
265-81.
Preisser, J.S., Galecki, A.T., Lohman, K.K., and Wagenknecht, L.E.
(2000) Analysis of smoking trends with incomplete repeated responses.
Journal of the American Statistical Association, 95, 1021-1031.
Fries, B.E., Morris, J.N., Skarupski, K.A., Blaum, C.S., Galecki, A.,
Bookstein, F., and Ribbe M. (2000) Accelerated Dysfunction Among the
Very Oldest-Old in Nursing Homes. Journal of Gerontology: Medical
Science, 55A, M336-M341.
Galecki, A.T. (1994) General class of covariance structures for two
or more repeated factors in longitudinal data analysis.
Communications in Statistics, 23, 3105-20.
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